Leukemia and thyroid cancer in emergency workers of the Chernobyl accident: estimation of radiation risks (1986-1995)

"Radiation and Risk" 1996. Vol. 8, pp. 47-58


Ivanov V.K., Tsyb A.F., Gorsky A.I., Maksyutov M.A., Rastopchin Eu.M., Konogorov A.P., Biryukov A.P., Matyash V.A.
Medical Radiological Research Center RAMS, Obninsk


The work focuses on direct epidemiological assessment of radiation risks in induction of leukemia and thyroid cancer in emergency workers after the Chernobyl accident. The Russian National Medical Dosimetric Registry compiles data for 168 thousand emergency workers as of 01.01.1996. Analysis is performed of 48 leukemias and 47 thyroid cancers diagnosed and verified in emergency workers. The estimated radiation risks are: for leukemia - excess relative risk per Gy (ERR/Gy) is 4,30 (95% CI = 0,83; 7,75), excess absolute risk per 104 PY Gy (EAR/104 PY Gy) is 1,31 (95% CI = 0,23; 2,39); and for thyroid cancer - ERR/Gy is 5,31 (95% CI = 0,04; 10,58), EAR/104 PY Gy is 1,15 (95% CI = 0,08; 2,22).

Key words
Direct epidemiological assessment, radiation risks, induction of leukemia, induction of thyroid cancers, liquidators, Chernobyl disaster.


1. Ivanov V.K., Tsyb A.F. Chernobyl radiation risks: assessments of morbidity, mortality and disability rates according to the data of the National Radiation and Epidemiological Registry. Proc. of Radiation and Human Health: Nagasaki symposium. - Amsterdam: Elsevier, 1996. - P. 31-48.

2. Ivanov V.K., Tsyb A.F., Rastopchin Eu.M., Maksyutov M.A., Gorsky A.I., Biryukov A.P., Chekin S.Yu., Konogorov A.P. Planning of long-term radiation and epidemiological research on the basis of the Russian National Medical Dosimetric Registry//Nagasaki symposium on Chernobyl update and future. - Amsterdam: Elsevier, 1994. PP. 203-216.

3. Ivanov V.K., Tsyb A.F., Maksyutov M.A., Rastopchin Eu.M., Gorsky A.I., Konogorov A.P., Chekin S.Yu., Pitkevich V.A., Mould R.F. Cancer morbidity and mortality among Chernobyl accident emergency workers residing in the Russian Federation//Current Oncology. 1995. No. 2. PP. 102-112.

4. Ivanov V.K., Tsyb A.F., Maksyutov M.A., Pitkevich V.A., Gorsky A.I., Rastopchin Eu.M., Korelo A.M., Chekin S.Yu., Konogorov A.P., Nilova E.V. Radiation epidemiological analysis of the data of the National Chernobyl Registry of Russia: prognostication and facts nine years after the accident. Radiation Protection Dosimetry. 1994. No. 64. PP. 121-128.

5. Cardis E., Anspaugh L., Ivanov V.K., Likthariev I., Mabuchi K., Okeanov A.E., Prisyazhniuk A. Estimated long term health effects of the Chernobyl accident. Proc. of the International Conference "One decade after Chernobyl: summing up the consequences of the accident". Background paper, session 3. Vienna, 1996.

6. Preston D.L., Kusumi S., Tomonaga M., Izumi S., Ron E., Kuramoto A., Kamada N., Dohy H., Matsui T., Nonaka H., Thompson D.E., Soda M., Mabuchi K. Cancer incidence in atomic bomb survivors. Part III: leukemia, lymphoma and multiple myeloma, 1950-1987. Radiat. Res. 1994. No. 137. PP. 68-97.

7. Health effects on populations of exposure to low levels of ionizing radiation. BEIR V Reports. Washington: US National Academy of sciences, 1990.

8. Malignant neoplasms in the Russian Federation in 1993. Collection of statistical materials. Ed. Acad. RAMS prof. V.I. Chissov, prof. V.V. Starinsky, Cand. med. sciences. L.V. Remennik. Part I. Moscow, 1995.

9. ICRP (International Commission on Radiological Protection). Recommendations of the International Commission on Radiological Protection. ICRP Report 60, Pergamon Press, Oxford, 1990.

10. Ron E., Lubin J.H., Shore R.E., Mabuchi K., Modan B., Pottern L.M., Schneider A.B., Tucker M.A., Boice J.D. Thyroid cancer after exposure to external radiation: a pooled analysis of seven studies. Radiat. Res. 1995. No. 141. PP. 259-277.

11. Shore R.E. Human thyroid cancer induction by ionizing radiation: summary of studies based on external irradiation and radioactive iodines. Proceedings of the first international conference "The radiological consequences of the Chernobyl accident". Minsk, Belarus, 1996. PP. 669-675.

Full text article (in Russian)