RADIATION & RISK
Bulletin of the National Radiation and Epidemiological Registry
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Effect of chronic electromagnetic radiation on embryogenesis and early postnatal development of the offspring of irradiated animals

«Radiation and Risk», 2021, vol. 30, No. 4, pp.61-68

DOI: 10.21870/0131-3878-2021-30-4-61-68

Authors

Panfilova V.V. – Sen. Res., C. Sc. Biol.
Kolganova O.I. – Sen. Res., C. Sc. Biol. Contacts: 4 Korolyov str., Obninsk, Kaluga region, Russia, 249035. Tel.: 8 (484) 399-71-38; е-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .
Chibisova O.F. – Researcher. A. Tsyb MRRC.
A. Tsyb MRRC, Obninsk

Abstract

The effect of electromagnetic radiation of the mobile communication frequency range during chronic exposure to the reproductive function of rats, the antenatal and postnatal development of the offspring of irradiated males and females Wistar rats was studied. Irradiation conditions: the carrier frequency 1800 MHz (unmodulated radiation), the power flux density of 85 μW/cm2, the zone of the formed wave (the distance from the radiation source of 1.3 m) from the radiation source. Males (15 individuals) and females (32 individuals) were exposed to radiation in an anechoic chamber in lattice containers for 1 hour a day, 5 days a week for 4 weeks. Two weeks after the last irradiation session the animals were paired at the rate of the one male for two females. Then pregnant female rats were irradiated from 5 to 17 days of pregnancy with the same exposure parameters. The animals of the control group (15 males and 30 females) were subjected to the same manipulation, but with the radiation source turned off. On the 20th day of pregnancy, some of females (13 experimental and 12 control females) were euthanized to study embryogenesis. To assess embryogenesis, the following factors were studied: ovulatory activity of the ovaries, preimplantation and postimplantation intra-uterine death of embryos, the average number of live fetuses, their cranio-caudal sizes and body weight. There was no difference between the experimental and control groups in embryogenesis. From the remaining 10 experimental and 14 control pregnant females, groups were formed to assess the postnatal development of the first generation offspring. No differences were found in the early postnatal ontogenesis of the offspring of irradiated and control animals. Thus, chronic unmodulated electromagnetic radiation with a frequency of 1800 did not have a significant effect on the course of pregnancy of the females and the early postnatal development of their first generation offspring.

Key words
mobile cellular communication, electromagnetic radiation, low intensity, anechoic chamber, Wistar rats, males, females, first generation offspring, embryogenesis, postnatal development.

References

1. Grigoriev Yu.G., Grigoriev O.A. Cellular communications and health. Electromagnetic environment. Radiobiological and hygienic problems. Hazard forecast. Moscow, Economics, 2015. 566 p. (In Russian).

2. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Non-ionizing radiation, Part 2: radiofrequency electromagnetic fields. IARC Monogr. Eval. Carcinog. Risks Hum., 2013, vol. 102, pp. 1-460.

3. Thomas S., Heinrich S., von Kries R., Radon K. Exposure to radio-frequency electromagnetic field and behavioral in Bavarian children and adolescent. Europ. J. Epidemiol., 2010, vol. 25, no. 2, pp. 135-141.

4. Jargin S.V. Hormesis and radiation safety norms: comments for an update. Hum. Exp. Toxicol., 2018, vol. 37, no. 11, pp. 1233-1243.

5. Sun C., Wei X., Fei Y., Su L., Zhao X., Chen G., Xu Z. Mobile phone signal exposure triggers a hormesis-like effect in Atm+/+ and Atm-/- mouse embryonic fibroblasts. Sci. Rep., 2016, vol. 6, p. 37423. DOI: 10.1038/step37423.

6. Internet 2017-2018 in the world and in Russia: statistics and trends. Available at: https://www.web-canape.ru/business/internet-2017-2018-v-mire-i-v-rossii-statistika-i-trendy/ (Accessed 28.04.2020). (In Russian).

7. Vershinin A.V., Avdonina L.A. The impact of cell phones on human health. Vestnic Pensenskogo Gosudar-stvennogo Universiteta – Bulletin of the Penza State University, 2015, no. 3, pp. 175-179. (In Russian).

8. Dulikov V.Z. Technologies of the 21st century and the socio-cultural sphere (achievements and miscalcula-tions). Vestnic Moskovskogo gosudarstvennogo universiteta kul'tury i iskusstva – Bulletin of the Moscow State University of Culture and Arts, 2010, no. 2, pp. 64-68. (In Russian).

9. Pronkevich M.D., Belkina S.V., Zhurakovskaya G.P. Defects of cells of animals, birds and plants after in vivo exposure to electromagnetic radiation of mobile phones. Certificate of registration of the database RU 2020620488 dated 16.03.2020. (In Russian).

10. Pronkevich M.D., Belkina S.V., Petin V.G., Vorobey O.A., Pereklad O.V., Zhurakovskaya G.P. Influence of mobile communications on human health disorders: non-carcinogenic effects. Certificate of registration of the database RU 2019622019 dated 08.11.2019. (In Russian).

11. Vereshchako G.G. Influence of electromagnetic radiation of mobile phones on the state of the male repro-ductive system and offspring. Minsk, Belarusian science, 2015. 190 p. (In Russian).

12. Khorseva N.I., Grigoriev Yu.G., Grigoriev P.E. Influence of low-intensity electromagnetic fields on the organisms’ antenatal development. Part 1. From gametogenesis to birth (review). Zhurnal mediko-biolog-icheskikh issledovanij – Journal of Biomedical Research, 2017, vol. 5, no. 4, pp. 42-54. (In Russian).

13. Khorseva N.I., Grigoriev Yu.G., Grigoriev P.E. Influence of low-intensity electromagnetic fields on the organisms’ antenatal development. Part 2. Late effects during the postnatal period (review). Zhurnal mediko-biologicheskih issledovanij – Journal of Biomedical Research, 2018, vol. 6, no. 1, pp. 41-55. (In Russian).

14. Grigoriev Yu.G. Biological effects of mobile phone electromagnetic field on chicken embryos (risk assessment using the mortality rate). Radiatsionnaya biologiya. Radioehkologiya. – Radiation Biology. Radioecology, 2003, vol. 43, no. 5, pp. 541-543. (In Russian).

15. Dasdag S., Akdag M.Z., Ulukaya E., Uzunlar A.K., Yegin D. Mobil phone exposure does induse apoptosis on spermatogenesis in rats. Arch. Med. Res., 2008, vol. 39, no. 1, pp. 40-44.

16. Zhavoronkov L.P., Dubovik B.V., Pavlova L.N., Kolganova O.I., Posadskaya V.M. The influence of wide-band pulse-modulated electromagnetic field of low-intensity on the whole excitability of the central nervous system. Radiatsiya i risk – Radiation and Risk, 2011, vol. 20, no. 2, pp. 64-74. (In Russian).

17. Ribeiro E.P., Rhoden E.L., Horn M.M., Rhoden C., Lima L.P., Toniolo L. Effects of subchronic exposure to radio frequency from a conventional cellular telephone on testicular function in adult rats. J. Urol., 2007, vol. 177, no. 1, pp. 395-399.

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