Hypertension incidence among workers at the Mayak nuclear complex

«Radiation and Risk», 2018, vol. 27, no. 2, pp.86-96

DOI: 10.21870/0131-3878-2018-27-2-86-96


Kuznetsova К.V. – Research Assistant. Southern Urals Biophysics Institute, FMBA of the Russian Federation, Ozyorsk, Russia. Contacts: 19 Ozyorskoe shosse, Ozyorsk, Chelyabinsk region, Russia, 456780. Tel.: 8 (35130) 2-93-20; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .
Azizova T.V. – Deputy Director, Head of Dep., C. Sc., Med. Southern Urals Biophysics Institute, FMBA of the Russian Federation, Ozyorsk, Russia.
Bannikova M.V. – Research Assistant. Med. Southern Urals Biophysics Institute, FMBA of the Russian Federation, Ozyorsk, Russia.


The objective this study is to estimate relative risk (RR) of hypertension incidence among the Mayak workers with protracted occupational exposure to ionizing radiation. The study cohort comprised 22,377 workers employed at one of the main plants between 1948 and 1982 and attended periodic medical examination up to 31.12.2013. All cohort members were exposed to external gamma-radiation and/or internal alpha-radiation due to their professional activities. Mean cumulative absorbed liver dose from external gamma-radiation was 0.45±0.65 Gy in males and 0.37±0.56 Gy in females; mean cumulative absorbed liver dose from internal alpha-particles was 0.23±0.65 Gy in males and 0.44±1.93 Gy in females. RR of hypertension was estimated using AMFIT module of EPICURE software. Hypertension was diagnosed in 8,425 cohort members, including 5,745 males and 2,680 females. Attained age, duration of employment, age at starting work, calendar years of employment, body mass index (BMI), and smoking status affected the risk values. Relative risk of hypertension was higher in workers with cumulative liver dose from external gamma-radiation >0.10 Gy. The risk of hypertension was significantly higher in workers with cumulative liver dose from internal alpha-radiation ranged between 0.10 and 0.15; 0.25 and 1.00 Gy than in workers with internal dose <0.01 Gy. The risk value increased with increase in cumulative liver dose from internal radiation. Relative risk of hypertension significantly depended on calendar period, age at starting work in the enterprise, employment duration, attained age, body mass index (BMI), smoking status as well as with cumulative absorbed liver dose from external gamma-rays and internal alpha-particles.

Key words
Hypertension incidence, cohort study, Mayak nuclear plant, nuclear workers, external gamma-radiation, internal alpha-radiation, protracted occupational exposure, cumulative dose, radiobiological effects, relative risk, medical examination.


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