Screening effect of breast cancer incidence among the population of Bryansk and Orel oblasts of the Russian Federation

«Radiation and Risk», 2016, vol. 25, No. 1, pp.25-33

Authors

Kashcheev V.V. – Head of Lab., C. Sc., Biol. A. Tsyb MRRC, Obninsk, Russia. Contacts: 4 Korolyov str., Obninsk, Kaluga region, Russia, 249036. Tel.: (484) 399-32-45; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .
Chekin S.Yu. – Head of Lab. A. Tsyb MRRC, Obninsk, Russia.
Maksioutov M.A. – Head of Lab., C. Sc., Tech. A. Tsyb MRRC, Obninsk, Russia.
Tumanov K.A. – Head of Lab., C. Sc., Biol. A. Tsyb MRRC, Obninsk, Russia.
Korelo A.M. – Senior Researcher. A. Tsyb MRRC, Obninsk, Russia.
Kochergina E.V. – Head of Lab., C. Sc., Med. A. Tsyb MRRC, Obninsk, Russia.
Vlasov O.K. – Head of Lab., D.Sc., Tech. A. Tsyb MRRC, Obninsk, Russia.
Shchukina N.V. – Senior Researcher. A. Tsyb MRRC, Obninsk, Russia.

Abstract

The study presents the estimations of screening effect for breast cancer among the population exposed as the result Chernobyl accident. The cohort selected for analysis consists of 127104 people from the most contaminated territories of Bryansk and Orel oblasts affected by the Chernobyl accident. Over the follow-up period 1996-2011, a total of 1164 breast cancer cases were identified as the result of annual compulsory health examination (1110 cases in Bryansk oblast and 54 cases in the Orel oblast). The study showed that the spontaneous cancer incidence of breast cancer among the population of Bryansk and Orel oblasts in the period from 1991 to 2011 was statistically lower (by 8%) than the level of incidence in Russia as a whole. Statistically significant screening effect on breast cancer detection was found in the most contaminated territories of Bryansk and Orel oblasts over the period 2006 to 2011. According to the WHO (2013) model of radiation the value of excess absolute risk in the selected cohort, the proportion of radiation-caused-morbidity may reach 1.2%.

Key words
Chernobyl accident, territory contaminated with radionuclides, population, cohort observation, radiation doses, breast cancer, incidence of disease, excess relative risk, standardized incidence ratio, screening.

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Full-text article (in Russian)