Modification of radiation-induced effects in animals and plants by excreted volatile substances

«Radiation and Risk», 2013, vol. 22, No. 2, pp.62-69


Kharlamov V.A. – Researcher, Medical Radiological Research Center of the Russian Ministry of Health, Obninsk. Contacts: 4 Korolyov str., Obninsk, Kaluga region, Russia, 249036. Tel.: (48439) 9-71-61; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .
B.P. – Head of Laboratory, D.Sc., Biol., Medical Radiological Research Center of the Russian Ministry of Health, Obninsk.


It is proved hat volatile substances excreted into urine of intact mice stimulate immune reactivity of spleen and regional lymph nodes in mice exposed to radiation at dose of 1 Gy. Seeds of agricultural plants both intact and exposed to radiation are found to be able to reciprocally modify initial growth parameters through aerial environment and sprouting medium. Modification of radiation-induced effects, common for both animals and plants, is thought to be carried out by the use of volatile chemosignals released by the species.

Key words
Bystander effect, ionizing radiation, mice, seeds of agricultural plants, volatile substances.


1. Es'kov E.K., Levin V.I. Spetsifichnost' distantsionnogo vozdeistviia g-obluchennykh semian rastenii na neobluchennye. Radiats. biol. Radioekologiia, 2002, vol. 42, no. 3, pp. 302-307.

2. Levin V.I. Agroekologicheskie aspekty predposevnoi obrabotki semian sel'skokhoziaistvennykh kul'tur gamma-luchami. Moscow: VNII «Agroekoinform», 2000. 221 p.

3. Surinov B.P., Dukhova N.N. Attraktivnye dlia intaktnykh osobei postradiatsionnye letuchie vydeleniia myshei. Radiats. biologiia. Radioekologiia, 2004, vol. 44, no. 6, pp. 662-665.

4. Surinov B.P., Isaeva V.G. Immunomoduliruiushchie effekty letuchikh vydelenii zhivotnykh pri postradiatsionnykh immunodefitsitnykh sostoianiiakh. Radiats. biologiia. Radioekologiia, 2008, vol. 48, no. 6, pp. 665-670.

5. Surinov B.P., Isaeva V.G., Dukhova N.N. Postradiatsionnye immunosupressiruiushchie i attraktivnye letuchie vydeleniia: «effekt soseda (baystander effect)» ili allelopatiia v gruppakh zhivotnykh. Doklady Akademii nauk, 2005, vol. 400, no. 5, pp. 711-713.

6. Mothersill C., Bucking C., Smith R.W. et al. Communication of radiation induced stress or bystander signals between fish in vivo. Environ. Sci. Technol., 2006, vol. 40, no. 21, pp. 6859-6864.

7. Nagasawa H., Little J.B. Induction of sister chromatid exchanges by extremely low doses of a-particles.

A defining paper of radiation-induced bystander responses in cellular models. Cancer Res., 1992, vol. 52,

pp. 6394-6396.

8. Yum E.H. W., Choi V.W.Y., Nikezic D. et al. Alpha-particle-induced bystander effects between zebrafish embryosin vivo. Radiation Measurements., 2009, vol. 44, pp. 1077-1080.

Full-text article (in Russian)