Ultrasound semiotics of cutaneous melanoma metastases in soft tissues and lymph nodes

«Radiation and Risk», 2008, vol. 17, no. 3, pp.38-45

Authors

Bashkatova T.A. – Doctor of ultrasound diagnostics. Medical Radiological Research Center of RAMS, Obninsk.

Parshin, V.S. – Department Head., M.D. Medical Radiological Research Center of RAMS, Obninsk. Contacts: 4 Korolyov str., Obninsk, Kaluga region, Russia, 249036. Tel.: (48439) 9-32-89; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .
Kudryavtseva G.T. – Department Head. M.D. Medical Radiological Research Center of RAMS, Obninsk.
Zakurdyaeva I.G. – Doctor. Medical Radiological Research Center of RAMS, Obninsk.

Abstract

In the presented study, ultrasound semiotics of cutaneous melanoma metastases in soft tissues and lymph nodes has been analyzed in 110 patients. Echography was performed on ultrasound Sonoline Antares (Siemens) equipment using linear 4-13 MHz transducers. Verification was done on the basis of aspiration biopsy and/or histological findings. Clinically invisible metastases were found in 35 % of cases. Ultrasonically, metastases were identified as a foreign tissue of low echogenicity against the background of the normal structure of the skin and soft tissues.

Key words
Ultrasound semiotics; metastases; cutaneous melanoma; lymph nodes; echography.

References

1. Anisimov V.V., Gordeladze A.S., Barchuk A.S., Wagner R.I. Skin Melanoma. SPb. Medicine Publ., 1996. 386 p.

2. Demidov L.V., Harkevich G.Yu. Melanoma of the skin: staging, diagnosis and treatment. Russian medical journal. 2003. Vol. 11, No. 11. PP. 658-665.

3. Merabishvili V.M. Malignant melanoma: modern trends (morbidity, mortality, diagnostics, morphological verification). Questions of Oncology. 2006. Vol. 52, No. 3. PP. 275-287.

4. Petrov G.V., Starinskiy V.V., Gretsova O.P., Kharchenko N.B. Epidemiology and state of cancer care for patients with melanoma in Russia. Russian Journal of Oncology. 2006. No. 1. PP. 41-45.

5. Chekalova M.A., Allahverdyan G.S., Demidov L.V. Preclinical diagnosis of skin melanoma metastases in regional lymph nodes. Ultrasound and Functional Diagnostics. 2003. No. 4. PP. 28-34.

6. Bataille V. Genetic epidemiology of melanoma. European Journal of Cancer. 2003. Vol. 39. PP. 1341-1347.

7. Eggermont A.M. Randomized trials in melanoma: an update. Surgical Oncology Clinics of North America. 2006. Vol. 15, No. 2. PP. 439-451.

8. Miller D.L., Dou C. The potential for enhancement of mouse melanoma metastasis by diagnostic and high-amplitude ultrasound. Ultrasound Med. Biol. 2006. Vol. 32, No. 7. PP. 1097-1101.

9. Spatz A. The role of the pathologist in the management of patient with melanoma. Меланома в глобаль-ной перспективе: фокус на Россию: Материалы Российской конференции с международным участием. Москва, 2007. С. 103-115.

10. Testori A., Lazzaro G. The role of ultrasound of sentinel nodes in the pre- and post-operative evaluation of stage 1 melanoma patients. Melanoma Res. 2005. Vol. 15, No. 3. PP. 191-198.

11. Vries E., Boniol M., Dore J.F. et al. Lower incidence rates thicker melanomas in Eastern Europe before 1992: a comparison with Western Europe. European Journal of Cancer. 2004. Vol. 40. PP. 1045-1052.

12. Vries E., Coebergh J.W. Cutaneous malignant melanoma in Europe. European Journal of Cancer. 2004. Vol. 40. PP. 2355-2366.

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