Thyroid cancer incidence among Chernobyl emergency workers: assessment of radiation risks

Issues

Authors

Chekin S.Yu., Kashcheev V.V., Tumanov K.A.
Medical Radiological Research Center of RAMS, Obninsk.

Abstract

A vast amount of research articles devoted to the increase in childhood thyroid cancer incidence in the most contaminated with radionuclides territories of Belarus, Russia and Ukraine affected by the Chernobyl accident were published in recent years. However, the amount of research studies of thyroid cancer incidence among the Chernobyl emergency workers (liquidators) is quite scanty. In the article results of the study of thyroid cancer incidence in the cohort of the Chernobyl liquidators (103427 persons) residing in 6 administrative regions of Russia (North-West, Volgo-Vyatsky, Central-Chernozemny, Povolzhsky, North-Caucasus and Urals) are described and discussed. For the period 1986-2003 eighty seven cases of thyroid cancer were detected in the cohort. Statistically significant excess of the incidence among liquidators over baseline incidence, SIR=3.39 (95% CI: 2.73; 4.16), among men of Russia has been found. At the same time no statistically significant relationship between the incidence rate and external radiation dose, ERR=1.68 (95% CI: -0.95; 6.46), was detected.

Key words
Incidence of cancer, thyroid gland, liquidators, assessment of radiation risks, Chernobyl accident, contaminated territories, radionuclides, cohort, statistically significant increase in incidence, external exposure dose.

References

1. Aleksakhin P.M., Buldakov L.A., Gubanov V.A. and others. Major radiation accidents: consequences and protective measures. Under the general ed. L.A. Ilyin and V.A. Gubanov. Moscow, Izdat Publ., 2001. 752 p.

2. Report of the United Nations Scientific Committee on the Effects of Atomic Radiation for 2000. Appendix J. Levels of exposure and effects from the Chernobyl accident. Trans. with English. A.A. Vainson, M.N. Mavkin and S.M. Shinkarev; Ed. Yu.S. Ryabukhin and S.P. Yarmonenko. Moscow, RADEKON Publ., 2001.

3. Cardis E., Kesminiene A., Ivanov V. et al. Risk of thyroid cancer after exposure to ¹³¹I in childhood. Journal of the National Cancer Institute. 2005. Vol. 97, no. 10. PP. 724-732.

4. Demidchik E.P., Mrochek A., Demidchik Yu. et al. Thyroid cancer promoted by radiation in young people of Belarus (clinical and epidemiological features). Radiation and thyroid cancer. Thomas G., Karaoglou A., Williams E.D. (eds). Proceedings of an international seminar on radiation and thyroid cancer. Brus-sels-Luxembourg: World Scientific, 1999. PP. 51-54.

5. Inskip P.D., Hartshorne M.F., Tekkel M. et al. Thyroid nodularity and cancer among Chernobyl cleanup workers from Estonia. Radiat. Res. 1997. V. 147. PP. 225-235.

6. Ivanov V.K., Gorski A.I., Pitkevitch V.A. et al. Risk of radiogenic thyroid cancer in Russia following the Chernobyl accident. Radiation and thyroid cancer. Thomas G., Karaoglou A., Williams E.D. (eds). Proceedings of an international seminar on radiation and thyroid cancer. Brussels-Luxembourg: World Scientific, 1999. PP. 89-96.

7. Ivanov V.K., Tsyb A.F., Gorsky A.I. et al. Thyroid cancer among "liquidators" of the Chernobyl accident. Brit. J. Radiol. 1997. Vol. 70. PP. 937-941.

8. Ivanov V.K., Tsyb A.F., Ivanov S.I. et al. Medical radiological consequences of the Chernobyl catastrophe in Russia: estimation of radiation risks. St. Petersburg: Nauka, 2004. 388 p.

9. Ivanov V.K., Tsyb A.F., Petrov A.V. et al. Thyroid cancer incidence among liquidators of the Chernobyl accident: absence of dependence of radiation risks on external radiation dose. Radiation and Environmental Biophysics. 2002. Vol. 41, no. 3. PP. 195-198.

10. Preston D.L., Lubin J.H., Pierce D.A. EPICURE User's Guide. Seattle: Hirosoft International Corp., 1992.

11. Tronko M., Bogdanova T., Komisarenko I. et al. The post-Chernobyl incidence of childhood thyroid cancer in Ukraine. Radiation and thyroid cancer. Thomas G., Karaoglou A., Williams E.D. (eds). Proceedings of an international seminar on radiation and thyroid cancer. Brussels-Luxembourg: World Scientific, 1999. PP. 61-70.

Full-text article (in Russian)