Issues
Radiation and epidemiological classification of complexes of the diseases of the human blood circulatory system, associated with the ionizing radiation in low doses
«Radiation and Risk», 2016, vol. 25, No. 4, pp.20-30
DOI: 10.21870/0131-3878-2016-25-4-20-30
Authors
Gorski A.I. – Lead. Researcher, C. Sc., Tech., A. Tsyb MRRC, Obninsk, Russia. Contacts: 4 Korolyov str., Obninsk, Kaluga region, Russia, 249036. Tel.: (484) 399-33-90; e-mail:
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.
Chekin S.Yu. – Head of Lab. A. Tsyb MRRC, Obninsk, Russia.
Maksioutov M.A. – Head of Lab., C. Sc., Tech. A. Tsyb MRRC, Obninsk, Russia.
Kashcheev V.V. – Head of Lab., C. Sc., Biol. A. Tsyb MRRC, Obninsk, Russia.
Kochergina E.V. – Head of Lab., C. Sc., Med. A. Tsyb MRRC, Obninsk, Russia.
Tumanov K.А. – Head of Lab., C. Sc., Biol. A. Tsyb MRRC, Obninsk, Russia.
Abstract
The article presents new type of classification of the circulatory system diseases associated with low-dose (< 1 Gy) radiation exposure. For analysis we used data obtained during the follow-up of 101614 Chernobyl clean up workers (liquidators) with average accumulated radiation dose of 0.1 Gy. For analysis of statistical links between radiation doses and structure of diagnosis of the circulatory system diseases we used methods of free a-priori probability distribution of doses and diagnoses. By comparing the structure of circulatory disease diagnoses in the dose group > 0.1 Gy with the same data in the dose group < 0.1 Gy, it turned out that such complex of diseases, as a) “Hypertensive heart disease without (congestive) heart failure” (I11.9) together with “Atherosclerotic heart disease” (I25.1) or “Hypertensive encephalopathy” (I67.4), or “Cerebral atherosclerosis” (I67.2), or “Other forms of angina pectoris” (I20.8); b) “Essential hypertension” (I10) with “Other forms of angina pectoris” (I20.8) or “Cerebral atherosclerosis” (I67.2) occurred more often in liquidators with dose > 0.1 Gy. Development of complex diseases, such as “Hypertensive heart disease without (congestive) heart failure” (I11.9) and “Essential hypertension” (I10) with other circulatory system diseases should be referred to the category of tissue reactions of a human body on the ionizing radiation exposure. For detected radiation-associated complexes of circulatory diseases farther circulatory diseases assessment of radiation risks with models for radiation epidemiological study of stochastic effects needed.
Key words
Ionizing radiation, low doses, Chernobyl liquidators, blood circulatory system diseases,
idiopathic hypertension, primary hypertension, structure of diseases, association rules, tissue
reactions, stochastic effects.
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