Radiation risks assessment of children cancer incidence based on computed tomography examination protocols

«Radiation and Risk», 2020, vol. 29, No. 2, pp.21-31

DOI: DOI: 10.21870/0131-3878-2020-29-2-21-31


Kashcheev V.V. – Head of Lab., C. Sc., Biol.
Pryakhin E.A. – Researcher. Contacts: 4 Korolyov str., Obninsk, Kaluga region, Russia, 249035. Tel.: (484) 399-32-81; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .
Menyajlo A.N. – Lead. Researcher, C. Sc., Biol.
Panin M.S. – Technician.
Seleva N.G. – Engineer.
Kashcheeva P.V. – Senior Researcher; C. Sc., Biol.
Ivanov S.A. – Director, MD, Prof. of RAS.
Ivanov V.K. – Deputy Director, Chairman of RSCRP, Corresponding Member of RAS. A. Tsyb MRRC.
Kaprin A.D. – General Director, Academician of RAS, MD, Prof. NMRRC.

A. Tsyb MRRC, Obninsk
1 NMRRC Russian Ministry of Health, Moscow


The article presents approach to estimating lifetime attributable risk (LAR) of cancer following single computed tomography (CT) scanning in childhood and adolescence. LAR estimating was two-stage process. First methods for calculating equivalent doses to organs and tissues were developed. For estimating LAR of solid cancer from computed tomography organ doses were calculated with the use of dose-length product (DLP) as a measure of absorbed dose. Coefficients for conversion of DLP for CT scans of thoracic, abdominal and pelvis organs to equivalent doses were evaluated. Risks of radiation-induced cancer from computed tomography in relation to age and sex were estimated for CT scans of thoracic and abdominal studies. Lifetime attributable risk of cancer was estimated with ICRP models (Publication 103) and medico-demographic parameters of the Russian population. LAR estimated using organ doses, evaluated with the use of DLP, were compared with the risk estimated with organ doses measured using silicone photodiode dosimeters.

Key words
radiation risk, exposure of children, medical exposure, computed tomography, organ doses, DLP, ICRP 103 Publication, lifetime attributable risk, single study, typical dose distribution.


1. Kashcheev V.V., Pryakhin E.A. Medical diagnostic imaging: radiation safety issues. Review. Radiatsiya i risk – Radiation and Risk, 2018, vol. 27, no. 4, pp. 49-64. (In Russian).

2. Zimatkina T.I., Malevich R.O., Volf S.B. Medical exposure of children and ways of optimization. Novosti mediko-biologicheskikh nauk – News of Biomedical Sciences, 2017, vol. 15, no. 1, pp. 14-19. (In Russian).

3. Communicating radiation risks in pediatric imaging: information to support health care discussions about benefit and risk. Geneva, WHO, 2016. 88 p.

4. IAEA Safety Standards. Radiation protection and safety of radiation sources: International Basic Safety Standards. General Safety Requirements No. GSR Part 3 (Interim). Vienna, IAEA, 2011.

5. Radiation Safety Standards (RSS-99/2009). Sanitary-epidemiological rules and standards. Moscow, Federal Center of Hygiene and Epidemiology of Rospotrebnadzor, 2009. 100 p. (In Russian).

6. Basic Sanitary Rules for Radiation Safety (OSPORB-99/2010). Health regulations, SP Moscow, Center for Sanitary and Epidemiological Rationing, Hygienic Certification of Russian Ministry of Health, 2010. (In Russian).

7. ICRP, 2007. The 2007 Recommendations of the International Commission on Radiological Protection. ICRP Publication 103. Ann. ICRP, 2007, vol. 37, no. 2-4, pp. 1-332.

8. Ivanov V.K., Tsyb A.F., Mettler F.A., Menyaylo A.N., Kashcheev V.V. Methodology for estimating cancer risks of diagnostic medical exposure: with an example of the risks associated with computed tomography. Health Phys., 2012, vol. 103, no. 6, pp. 732-739.

9. Ivanov V.K., Menyailo A.N., Kashcheev V.V., Chekin S.Yu., Gorsky A.I., Maksioutov M.A., Tumanov K.A. Comparative analysis of modern risk models developed by ICRP and UNSCEAR. ANRI, 2011, no. 3, pp. 18-29. (In Russian).

10. Malignant neoplasms in Russia in 2008 (morbidity and mortality). Eds.: V.I. Chissov, V.V. Starinskiy. Moscow, 2010. (In Russian).

11. Monitoring of effective doses to patients during medical x-ray studies: guidelines. Moscow, Federal Center for Hygiene and Epidemiology of Rospotrebnadzor, 2011. 38 p.

12. European guidelines on quality criteria for computed tomography. EUR 16262. Luxembourg, Office for Official Publications of the European Communities, 2000.

13. Shrimpton P.C., Hillier M.C., Lewis M.A., Dunn M. National survey of doses from CT in the UK: 2003. Br. J. Radiol., 2006, vol. 79, no. 948, pp. 968-980.

14. Stamm G., Nagel H.D. CT-expo: a novel program for dose evaluation in CT. Rofo., 2002, vol. 174, no. 12, pp. 1570-1576.

15. Fujii K., Aoyama T., Yamauchi-Kawaura C., Koyama S., Yamauchi M., Ko S., Akahane K., Nishizawa K. Radiation dose evaluation in 64-slice CT examinations with adults and paediatric anthropomorphic phan-toms. Br. J. Radiol., 2009, vol. 82, no. 984, pp. 1010-1018.

Full-text article (in Russian)