RADIATION & RISK
Bulletin of the National Radiation and Epidemiological Registry
since 1992
About the Journal : 2013 : vol. 22, No. 3 : Postoperative radiation therapy for prevention of breast cancer local recurrencee

Postoperative radiation therapy for prevention of breast cancer local recurrencee

«Radiation and Risk», 2013, vol. 22, No. 3, pp.72-79

Authors

Startseva Zh.A. – Head of the Radiology Department, MD, Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk.
Velikaya V.V. – Research Assistant, C. Sc., Med., Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk.
Simonov K.A. – Postgraduate Student, Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk. Contacts: 5 Kooperativny L., Tomsk, 634009. Tel.: 8 (3822)42-00-62; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .
Musabaeva L.I. – Chief Researcher, MD, Prof., Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk.

Abstract

Between  2005  and  2012,  a  total  of  162  patients  with operable breast cancer (T2-4N0-3M0-1) were treated with neo- and adjuvant chemotherapy, radical mastectomy, postoperative external beam radiotherapy with the use of densely ionizing radiation delivered to the area of the anterior thoracic wall including postoperative scar and external beam radiotherapy to the areas of potential cancer spread. Adjuvant radiation therapy delivered to the area of the anterior chest wall and postoperative scar served as a good prevention of local recurrence of breast cancer. Postoperative neutron  therapy  was  effective  in  patients with locally advanced breast cancer. The 5-year recurrence-free survival for neutron and electron therapies were 93.6±4.3% and 93.8±3.5%, respectively. The 5-year recurrence-free survival was 80±6.1% in patients who received radiation therapy delivered only to the areas of potential cancer spread without radiotherapy of postoperative scar.

Key words
Cancer, recurrence, adjuvant radiation therapy, neutron therapy.

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