Psychophysiological development of the first and second generations of male rats exposed to radiation of 1.5 Gy

«Radiation and Risk», 2013, vol. 22, No. 2, pp.101-109

Authors

Panfilova V.V. – Postgraduate Student, Medical Radiological Research Center of the Russian Ministry of Health, Obninsk. Contacts: 4 Korolyov str., Obninsk, Kaluga region, Russia, 249036. Tel.: (48439) 9-71-38; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .
Kolganova O.I. – Senior Researcher, C. Sc., Biol., Medical Radiological Research Center of the Russian Ministry of Health, Obninsk.
Zhavoronkov L.P. – Head of Dep., MD, Medical Radiological Research Center of the Russian Ministry of Health, Obninsk.
Pavlova L.N. – Lead. Researcher, C. Sc., Med., Medical Radiological Research Center of the Russian Ministry of Health, Obninsk.
Palyga G.F. – Main Researcher, MD, Medical Radiological Research Center of the Russian Ministry of Health, Obninsk.
Chibisova O.F. – Research Assistant, Medical Radiological Research Center of the Russian Ministry of Health, Obninsk.

Abstract

Effect  of  exposure  of  rat  males  to  gamma-radiation  at  dose  of  1.5 Gy,  dose rate 3·10-3 Gy/s on psychophysiological development of their first and second generations was studied. The rats were exposed to radiation at different stages of spermatogenesis. Cognitive function of brain in both generations was tested using shuttle-box avoidance method. Irradiation of male rats at all stages of spermatogenesis produced negative effect on the first generation, the adverse radiation-induced effect on the second generation was less pronounced.

Key words
Rats, brain cognitive functions, gamma-irradiation, Shuttle-box, spermatogenesis.

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