RADIATION & RISK
Bulletin of the National Radiation and Epidemiological Registry
since 1992
About the Journal : 2012 : vol. 21, No. 2 : Comparison of biological effectiveness of pulse and continuous radiation of 14 MeV neutrons on murine melanoma B-16 cell culture

Comparison of biological effectiveness of pulse and continuous radiation of 14 MeV neutrons on murine melanoma B-16 cell culture

«Radiation and Risk», 2012, vol. 21, no. 2, pp.83-90

Authors

Isaeva E.V. – Senior Researcher, C. Sc., Biol.,Medical Radiological Research Center of the Russian Ministry of Health and Social Development, Obninsk.
Beketov E.E. – Postgraduate Student,Medical Radiological Research Center of the Russian Ministry of Health and Social Development, Obninsk.
Koryakin S.N. – Leading Researcher, C. Sc., Biol.,Medical Radiological Research Center of the Russian Ministry of Health and Social Development, Obninsk.
Ulianenko S.E. – Head of Dep., D. Sc., Biol.,Medical Radiological Research Center of the Russian Ministry of Health and Social Development, Obninsk. Contacts: 4 Korolyov str., Obninsk, Kaluga region, Russia, 249036. Tel.: (48439) 9-72-10; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .

Abstract

The effect of pulse (10, 50, 75 Hz) and continuous radiation of 14 MeV neutrons in 0.5-5 Gy dose range on melanoma B-16 cells clonogenic growth was studied. Obtained results show no difference in biological effectiveness of pulse radiation of different frequencies. Clonogenic assay of murine melanoma B-16 cells did not show a difference between effects of pulse and continuous radiation modes within studied dose range.

Key words
Рulse and continuous neutron irradiation, melanoma B-16.

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