RADIATION & RISK
Bulletin of the National Radiation and Epidemiological Registry
since 1992
About the Journal : 2011 : vol. 20, No. 4 : Experimental estimation of the combined effects of radiation and external hypothermia on pregnancy and development of posterity of two generations of Wistar rats

Experimental estimation of the combined effects of radiation and external hypothermia on pregnancy and development of posterity of two generations of Wistar rats

«Radiation and Risk», 2011, vol. 20, no. 4, pp.54-63

Authors

Ivanov V.L. – Senior Researcher, C. Sc., Vet. Medical Radiological Research Center of the Russian Ministry of Health and Social Development, Obninsk.
Chibisova O.F. – Research Assistant. Medical Radiological Research Center of the Russian Ministry of Health and Social Development, Obninsk.
Palyga G.F. – Main Researcher, MD, Prof. Medical Radiological Research Center of the Russian Ministry of Health and Social Development, Obninsk. Contacts: 4 Korolyev str., Obninsk, Kaluga region, Russia, 249036. Tel.: (48439) 9-70-45; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .

Abstracts

Effects of single whole-body irradiation of Wistar rats at different stages of ovogenesis with 60Co at dose of 2.0 Gy (dose-rate 0.2 Gy/min) under lasted external hypothermia (+10oС and +5oС) on course of pregnancy and development of posterity of two generations were studied. The irradiation during ovulation was found to effect on pregnancy course and physical development of posterity of the first generation under  comfortable  temperature  in  an  environment  (+22oС). The irradiation of rats 4-11 and 30-40 days prior to their fertilization did not effect on the studied indicators. Hypothermia produced certain effect on dynamics of parameters, depending on the period of pregnancy. Irradiation of rats Fo at ovulation did not effect significantly on pregnancy of the first generation females and physical development of the second generations. However, there was tendency to reduction of survival of rats to the 28th day of their life.

Key words
Wistar rats, irradiation, external hypothermia, pregnancy, posterity.

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Full-text article (in Russian)