Certain regularities of adaptive response of dividing populations of Saccharomyces cerevisiae to ionizing radiationyroid abnormalities among children of the south-west area of the Kaluga oblast exposed to radiation in utero during different periods of gestation

«Radiation and Risk», 2006, vol. 15, no. 1-2, pp.59-67


Gorshkova T.A.
Medical Radiological Research Center of RAMS, Obninsk.


The results of adaptive response investigation for dividing cell populations of diploid yeast Saccharomyces cerevisiae are presented. The existence of both the smallest dose rate producing the adaptive response and the range of doses and dose rates of γ-radiation within which the adaptive response to the following irradiation was the highest. The adaptive response of dividing yeast cells was registered by pretreatment not only by low but also high damaging doses. Adaptive response was expressed in increase of survival and in acceleration of colony appearance produced by irradiated cells.

Key words
Adaptive response, population of diploid yeast cells, Saccharomyces cerevisiae, threshold dose rate, γ-radiation, dose interval, dose-damaging, survival.


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