Radio-epidemiological analysis of incidence of non-cancer diseases among the Chernobyl liquidators

"Radiation and Risk". 2001. Vol. 12, pp.82-98

Authors

Ivanov V.K., Maksioutov M.A., Chekin S.Yu., Kruglova Z.G., Petrov A.V., Tsyb A.F., Ivanov S.I.1
Medical Radiological Research Center of RAMS, Obninsk.
1Ministry of Health Care of Russian Federation, Moscowа.

Abstract

The work is concerned with assessment of radiation risks for non-cancer diseases among the Chernobyl liquidators from 1986 to 1996. As of 1 January 1999, the Russian National Medical and Dosimetric Registry contains medical and dosimetric data for 174 thousand liquidators. The cohort of 68309 liquidators for whom best verified medical data are available is discussed. The dose dependency of incidence of non-cancer diseases was estimated by the cohort method and using the software package EPICURE. For some classes of non-cancer diseases among liquidators statistically significant estimates of radiation risk were derived for the first time. The highest excess relative risk per 1 Gy was found for cerebrovascular diseases ERR/Gy=1.17 at the 95% confidence interval (0.45; 1.88).

Key words
Assessment of radiation risks, dynamics of non-oncological diseases, liquidators, Chernobyl NPP, non-oncological diseases, dose dependence, cohort method.

References

1. Buzunov V., Omelyanetz N., Strapko N. et al. Chernobyl NPP accident consequences cleaning up participants in Ukraine - health status epidemiologic study - main results. The Radiological Consequences of the Chernobyl Accident. Luxembourg: Office for Official Publications of the European Communities, 1996. PP. 871-878.

2. Ivanov V.K., Tsyb A.F., Gorsky A.I. et al. Leukaemia and thyroid cancer in emergency workers of the Chernobyl accident: estimation of radiation risks (1986-1995). Radiat. Environ. Biophys. 1997. Vol. 36. PP. 9-16.

3. Ivanov V.K., Rastopchin E.M., Gorsky A.I., Ryvkin V.B. Cancer incidence among liquidators of the Chernobyl accident: solid tumors, 1986-1995. Health Phys. 1998. Vol. 74, no. 3. PP. 309-315.

4. Okeanov A.E., Cardis E., Antipova S.I. et al. Health status and follow-up of the liquidators in Belarus. The Radiological Consequences of the Chernobyl Accident. Luxembourg: Office for Official Publications of the European Communities, 1996. PP. 851-859.

5. Rahu M., Tekkel M., Veidebaum T. et al. The Estonian study of Chernobyl cleanup workers: II. Incidence of cancer and mortality. Radiation Res. 1997. Vol. 147. PP. 653-657.

6. Wong F.L., Yamada M., Sasaki H. et al. Noncancer diseases incidence in atomic bomb survivors: 1958-1986. Radiation Res. 1993. Vol. 135. PP. 418-430.

Full-text article (in Russian)