Analysis of incidence and mortality for malignant neoplasms of the digestive system among the liquidators in 1986-1997

"Radiation and Risk". 2001. Vol. 12, pp.62-81


Biryukov A.P., Ivanova I.N., Gorsky A.I, Petrov A.V., Matyash V.A.
Medical Radiological Research Center of RAMS, Obninsk.


In this paper, we analyze information on morbidity and mortality from malignant neoplasms of the digestive system of participants in the liquidation of the consequences of the Chernobyl accident (liquidators) accumulated in the Russian State Medical Dosimetric Registry (RGMDR) from 1986 to early 1998. data on male liquidators registered in the six regional centers of the RSMDR, which annually supply the most calibrated medical dosimetry data: North-West, Volga-Viat Central Black Earth, Volga, North-Caucasian and Urals. The number of such liquidators is 96026 people, which is 57% of all registered participants in the RGMDR of liquidation of the consequences of the Chernobyl accident. The average dose in the studied cohort of liquidators is & ndash; 108 mGy, the average age at the time of entry into the work area is 34.3 years, the total accumulated number of person-years & ndash; 1011727. The levels of cancer morbidity and mortality by tumors of the digestive system of the liquidators and the population of Russia as a whole are compared by calculating the standardized ratio of morbidity (SIR) and mortality (SMR). SIR and SMR values ​​with 95% confidence intervals for malignant neoplasms of the digestive system were 0.88 (0.80, 0.97) and 0.72 (0.64, 0.80), respectively. For the 1986 liquidators of entry into the zone Works - 0.97 (0.85, 1.11) and 0.81 (0.70, 0.94) respectively. During the observation period from 1991 to 1997, when the SIR of the liquidators became stable, the SIR and SMR values ​​with 95% confidence intervals for malignant neoplasms of the digestive system were 1.00 (0.90, 1.10) and 0.87 ( 0.78, 0.98), respectively. For the liquidators of 1986, entering the work area & ndash; 1.15 (1.00, 1.33) and 1.02 (0.86, 1.19), respectively. Assessment of radiation risks for this class of diseases did not reveal a statistically significant increase in cancer morbidity or mortality with an increase in the dose of external irradiation of the liquidators.

Key words
Morbidity, mortality, malignant neoplasms, digestive system, participants in the elimination of the consequences of the accident, Chernobyl nuclear power plant, liquidators, cohort, tumors.


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