Intraoperative radiotherapy in the combined treatment of breast cancer

«Radiation and Risk», 2009, vol. 18, no. 2, pp.82-89

Authors

Medvedev F.V. – Surgeon. Medical Sciences Medical Radiological Research Center of the Russian Academy of Medical Sciences, Obninsk. Contacts: 4 Korolyov str., Obninsk, Kaluga region, Russia, 249036. Tel.: (48439) 9-31-48; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .
Gulidov I.A. – Chief of Department, D.Sc., Medicine, Professor. Medical Sciences Medical Radiological Research Center of the Russian Academy of Medical Sciences, Obninsk.
Smirnova I.A. – Team manager, D. Sc., Medicine. Medical Sciences Medical Radiological Research Center of the Russian Academy of Medical Sciences, Obninsk.

Abstract

The results of treatment of 120 patients with breast cancer using intraoperative radiotherapy (IORT) in combination with organ saving surgery and distant radiotherapy are given in this report. IORT was made on the Russian cyclic electron accelerator “Microtron-M”. The removed tumor bed area or axillary region was irradiated. The single focal irradiation dose was 10 Gy, while the accelerated electrons energy was 8 MeV. The obtained results analysis indicated that using of IORT doesn’t increase the frequency of postoperational complications, radiation responses and injuries, extends the indications for organ saving operations on mammary gland, doesn’t worsen the survival rate indices and can be considered as the alternative to the intensive preoperational irradiation.

Key words
IORT, breast cancer, organ saving surgery.

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Full-text article (in Russian)