Experimental and clinical researches of possibility of electrochemical lysis in treatment of malignant tumors

«Radiation and Risk», 2009, vol. 18, no. 2, pp.61-73

Authors

Kaplan M.A. – Head of Department, D.Sc., Medicine, Professor. Medical Radiological Research Center of the Russian Academy of Medical Sciences, Obninsk.
Medvedev V.N. – Chief of Department, Cand.Sc., Medicine. Medical Radiological Research Center of the Russian Academy of Medical Sciences, Obninsk.
Kiseleva M.V. – Chief of Department, D.Sc., Medicine. Medical Radiological Research Center of the Russian Academy of Medical Sciences, Obninsk.
Malik S.S. – Doctor, Cand.Sc., Medicine. Medical Radiological Research Center of the Russian Academy of Medical Sciences, Obninsk.
Kapinus V.N. – Doctor, Cand.Sc., Medicine. Medical Radiological Research Center of the Russian Academy of Medical Sciences, Obninsk.
Goranskaya E.V. – Research Assistant. Medical Radiological Research Center of the Russian Academy of Medical Sciences, Obninsk. Contacts: 4 Korolev str., Obninsk, Kaluga region, Russia, 249036. Tel.: (48439) 9-30-26; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .
Mikhailovskaya A.A. – Research Assistant.
Taibova M.V. – Doctor. Medical Radiological Research Center of the Russian Academy of Medical Sciences, Obninsk.
Fomin S.D. – Doctor. Medical Radiological Research Center of the Russian Academy of Medical Sciences, Obninsk.

Abstract

In experiment an antitumoral efficiency of electrochemical lysis (ECL) was estimated on an example sarcoma M-1, some various combination of ECL parameters (current strength, time of influence) were investigated. By estimate of results we can see that with increase of parameters a percent of full tumor regression goes up. It was confirmed by investigation of the morphological section. In clinic by performance of ECL to patient with breast cancer the medicinal pathomorphism 3 stages was achieved. In observation period we haven’t received the date about metastasis.

Key words
Electrochemicallysis, sarcoma M-1, cancer.

References

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